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Angelman Syndrome

What is Angelman Syndrome?

A Rare Genetic Disorder

Angelman syndrome (AS) is a rare genetic disorder that affects the nervous system. It is characterized by intellectual disability, developmental delay, seizures, and a happy demeanor. AS is caused by a deletion or mutation of the UBE3A gene on chromosome 15.

Symptoms of Angelman Syndrome

The symptoms of AS can vary from person to person, but they typically include:

  • Intellectual disability
  • Developmental delay
  • Seizures
  • Happy demeanor
  • Speech and language problems
  • Motor problems
  • Sleep problems
  • Feeding problems

Causes of Angelman Syndrome

AS is caused by a deletion or mutation of the UBE3A gene on chromosome 15. The UBE3A gene provides instructions for making a protein that is essential for the proper development of the nervous system. When the UBE3A gene is deleted or mutated, the protein is not produced, which leads to the symptoms of AS.

Treatment for Angelman Syndrome

There is no cure for AS, but there are treatments that can help to manage the symptoms. These treatments may include:

  • Medication to control seizures
  • Speech and language therapy
  • Physical therapy
  • Occupational therapy
  • Special education

Conclusion

Angelman syndrome is a rare genetic disorder that affects the nervous system. It is characterized by intellectual disability, developmental delay, seizures, and a happy demeanor. AS is caused by a deletion or mutation of the UBE3A gene on chromosome 15. There is no cure for AS, but there are treatments that can help to manage the symptoms.

If you think your child may have Angelman syndrome, it is important to see a doctor for an evaluation. Early diagnosis and treatment can help to improve your child's quality of life.


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